产品货号：
Z24923
中文名称：
RIPK1抗体
英文名称：
Anti-RIPK1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-RIPK1 Antibody |
| 指标别名 | Cell death protein RIP;Receptor interacting protein 1;RIP;RIP 1;RIP1;RIPK1;RIPK1-Specific |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | RIPK1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | RIPK1 antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human RIPK1.The immunogen is located within amino acids 180 - 230 of RIPK1. |
| 计算分子量 | 76kDa |
| 成分 | RIPK1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | RIPK1 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | RIPK1 (Receptor Interacting Protein) is a crucial 74kD adaptor kinase in several of stress-induced signaling pathways and on the crossroad of a cell's decision to live or die.RIPK1 contains an N-terminal region with homology to protein kinases,an intermediate domain capable of association with MAPKKK and a C-terminal region containing a death domain motif present in the Fas and TNFR1 intracellular domains.Full length RIPK1 is important for signallling to NF百-B,MAPKs and necrosis,whereas caspase-8 generates a C-terminal RIPK1 cleavage fragment,promoting TNF-induced apoptosis.It is required for TNFRSF1A-mediated and TLR3-induced NF-百B activation.RIPK1-deficient mice fail to thrive,displaying extensive apoptosis in both lymphoid and adipose tissues and dying at 1-3 days of age. |
| Uniprot ID | Q13546 |
| 基因名全称 | Receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| 蛋白名全称 | Receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| 推荐稀释比 | RIPK1 antibody can be used for detection of RIPK1 by Western blot at 1μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in rat samples;Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples.All other applications and species not yet tested. |
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